Funding
Novel Roles of Placental Allopregnanolone in Brain Development and Injury
This grant supports the use of new molecular and mouse models to test the role of key placental hormones in normal brain development and how their loss may contribute to injury.
Sponsor: NIH/NICHD
Grant Type: R01
PI: Anna A. Penn, MD/PhD
District of Columbia Intellectual and Developmental Disabilities Research Center
The mission of the DC-IDDRC is to expand our understanding of the causes underlying intellectual and developmental disabilities (IDD), develop innovative therapies, and prevent or attenuate these disorders. Collaborating DC academic medical centers (Children’s National Health System (lead), George Washington University, Howard University, and Georgetown University) work together to promote translational research and training opportunities, supported by the Clinical Translational Core (CTC) which provides assistance at each stage of the clinical and translational research spectrum and optimizes efficient, high quality implementation of fundamental research.
Sponsor: NIH/NICHD
Grant Type: U54
PI: Vittorio Gallo, PhD
Protection and Repair of Preterm Cerebellum by Allopregnanolone
This grant supports cord blood hormone measurements across gestational ages, longitudinal assessment of neonatal hormone levels in extremely preterm infants and preclinical hormone treatment assessment
Sponsor: Research Foundation of Cerebal Palsy Alliance
Grant Type: Foundation
PI: Anna A. Penn, MD, PhD
Board of Visitors Perinatal Neuroprotection Program
This grant supports development of multi-disciplinary team focused on improving outcomes in extremely preterm infants, including support for preterm neurological monitoring, preclinical investigation of neuroprotective hormones and specialized fellow training at Children’s National Medical Center.
Sponsor: Board of Visitors
Grant Type: Foundation
PI: Anna A. Penn, MD, PhD
Linking Preterm Birth and ASD risk with cerebellar white matter
This grant focuses on how placental ALLO insufficiency impairs cerebellar myelination and to compare Akr1c14plKO cerebellar network alterations to established ASD models.
Sponsor: SFARI (Simons Foundation)
Grant Type: Foundation
PI: Anna A. Penn, MD, PhD